Worse-than-average chromosomal abnormalities

Hi, I don’t think your results are enough to conclude you have a worse than normal rate of abnormal embryos. The % are stats and with such small numbers like we have in IVF embryos, it can easily swing. Here you have 33% normal, but with a bit of luck, if you had two normal , you would have had 66% normal. If everyone had 3 embryos, some will have 1 normal, some 2 normal, and the average between all of us will be around 50% if that makes sense ? I think it’s just bad luck that for this retrieval you had one normal rather than two. I saw a couple people sharing their success stories with only one embryo - this one could be the one for you 😊

Thanks Annia, yes fingers crossed this one would indeed work out well in the end! 🤞🏻 🤞🏻 Just that I also wanted two children, so not sure what to do next, especially as the normalities get worse with age. But maybe we will just do this transfer first and see how we get on after. Thanks for your comments 🙂

Of course. I really hope your embryo sticks ❤️

It can be variable from one collection to the next. Here are my numbers: Egg collection aged 38: 25 eggs 22 mature 17 fertilised 7 blastocysts 1 normal embryo by PGTA (that embryo is now a boisterous toddler 😁) Egg collection aged 41: 15 eggs (Can’t remember maturity or fertilisation rate, even though more recent 🤦🏻‍♀️) 6 blastocysts 4 embryos normal by PGTA (can’t remember the gradings, but I think a mix of 4-5 and A-B) The results blew my mind a bit as I didn’t expect better results being 3 years older and with fewer eggs collected. The clinic didn’t really suggest a reason, but said every collection is different. It was the same protocol for both collections and I haven’t really had any health changes during that time. Best of luck, the whole process is so unpredictable isn’t it.

Thank you Rose for sharing your results that's really reassuring to know! Yes I suppose it could all just be random. What happened after with your second egg collection, did you do a transfer and had another healthy child/children? Thank you, I'm so nervous about everything and wasn't sure how I felt about the PGT-A results. But suppose 1 is at least something and hopefully it all sticks! 🤞🏻

I couldn't really understand also because my amh is 17.3 but we only collect 8 eggs and out of those 6 were mature. I was expecting more eggs to grow and to be collected.

Glad it’s reassuring. My egg collection was in July, I’ve had my first scan of a frozen cycle today (I delayed the transfer for a month as we were on holiday).

All the best for you too for your transfer next cycle!

I think which FSH drug they use makes a difference to how your body responds re egg collection. There's the Alpha/Beta/Delta variants and they sort of guess which one to use x

Thanks Amelia that's interesting to know. Mine was Meriofert, I'm not sure which of those is that. Does that impact egg quality as well or is that just a random chance, you think? I saw someone mentioned she changed clinic and protocol/medication and went from 0 blastocysts from a first transfer, to 11 great quality ones 2 years later , with the changes.

Wow that's a big change in success rates! I don't think it impacts quality of the eggs but I think it impacts the rate at which they develop if that makes sense x